CEC 5

Nanotoxicology and risk assessment: the state of the art

Programme of the Session

10:00 – 10:15	CE course opening and introduction
10:15 – 11:00	Improving the OECD test guidelines to better address inhalation toxicity assessment of nanomaterials Ken Moss United States Environmental Protection Agency, United States
11:00 – 11:45	Principles and Methods for assessing the risk of immunotoxicity associated with exposure to nanomaterials: New WHO guidance Henk van Loveren Maastricht University, The Netherlands
11:45 – 12:00	Discussion
12:00 – 13:00	Lunch Break
13:00 – 13:45	Nanomaterials and cancer: what do we know? Dawson Kenneth School of Chemistry and Chemical Biology, Science Centre South, University College Dublin, Ireland
13:45 – 14:30	Availability of methods for characterising the physical-chemical properties of nanomaterials: implications for hazard identification, read-across and risk assessment Juan Riego Sintes Joint Research Centre of the European Union, Italy
14:30 – 15:15	Missing elements for regulatory testing and assessments of nanomaterials, and research needs Camelia Constantin ECHA - European Chemicals Agency, Finland
15:15 – 16:00	Discussion and Closing of the CEC course

Session Abstract

There are growing concerns that exposure to nanoparticles may pose adverse health impacts, and that the adverse effects are greatly influenced by the small size and size-associated properties of nanoparticles. A decade of nanotoxicology research has clearly established that nanoparticles predominantly induce inflammatory response. Other effects may include adjuvant activity of allergic responses, neurological effects, reproduction effects, and genotoxicity resulting in carcinogenicity; some of these endpoints may in fact depend on inflammatory events occurring after exposure to nanoparticles. This symposium aims to summarize the state of the art for risk assessment, and identify missing elements and research needs.

Discussion and Closing of the CE course